Mesenchymal stem cells are the basic agent in regenerative medicine. They are responsible for treating, repairing or restoring function to lost tissue as a result of injury, sickness, old age or congenital defects. Mesenchymal stem cells are multi-potent stem cells capable of self-renewal and differentiation in several cellular types – bone cells, cartilage, tendon, muscle cells, fat cells. They may also be converted into target tissue or impact on the surrounding cells. Owing to the secretion of a wide variety of factors, they act on adjacent cells either by directly initiating repair mechanisms inside the damaged cells or indirectly by facilitating interaction between various types of cells leading to the regeneration of damaged tissue and elimination of inflammation. As such the stem cells activate and encourage the body to activate its own natural treatment. Providing they are applied directly to the affected area; for instance joints, they inhibit the creation of osteophytes (ossified growths worsening joint pain), reduce the degeneration of cartilage and stimulate the growth of cartilage cells. When stem cells are applied to an injured tendon, the tissue heals very well and its function is fully restored.

 

Studies around the world are currently underway focusing on the use of stem cells to treat diabetes, damage to the heart, nervous tissue, the corneas, regeneration of the kidneys and liver. Data acquired from the field of veterinary practice and pre-clinical research, however, confirms the potential of cellular therapy and form the basis for further research and clinical trials in humans.kmenove bunky a vyzkum 01


Did you know about stem cells? - news from the world of stem cells

diabetesDiabetes is a very common disease and the number of patients (above all children) diagnosed with type 1 diabetes is constantly on the rise. Scientific research centres are now looking at ways to grow stem cells in a lab using beta cells (insulin producing cells) which should resolve the current issue of acquiring a sufficient number of quality Langerhans islets (pancreatic area containing beta cells) for transplantation.

http://www.eurostemcell.org/factsheet/diabetes-how-could-stem-cells-help

parkinsonParkinson's disease affects millions of people worldwide. Right now we know how to alleviate the symptoms of the disease but we still don't have a drug for it. University and research institutes are busy investigating the use of stem cells to treat this neurodegenerative disease. Nerve cells are grown from stem cells in a laboratory and transplanted directly to the damaged area or the destroyed neurons in the brain. Tests are currently being conducted on animals, however scientists anticipate that the first clinical tests on humans could take place as early as 2017 or 2018.

http://www.eurostemcell.org/factsheet/parkinsons-disease-how-could-stem-cells-help

artrozaAn extensive clinical study got underway in 2015 testing the use of adult stem cells to treat osteoarthritis in humans. A total of ten hospitals in 6 European countries took part in the study whereby a total of 150 patients were tested.

http://www.eurostemcell.org/story/trial-test-stem-cells-knee-osteoarthritis